Figure 7.

The curcuminoid in a low-dose regimen administered to diabetic rats for 14 days was shown to have a markedly hypoglycaemic effect, accompanied by an improvement of the lipidic profile, which promoted better metabolic control. Furthermore, this new molecule was able to enhance the relaxation response in the aorta, along with a reduction in the vascular oxidative and nitrosative stress, suggesting an improved endothelial function and vascular homeostasis, which may contribute to the prevention of diabetic complications.