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Differences between mAb and Ligands.
| Ligand (PSMA 617) | mAb (J591) |
|---|---|
| Small (mw 1400) | Large (mw 150,000) |
| Short circulation time | Long circulation time (days) |
|
|
| Rapidly diffuse to all sites of expression | Mostly target via vasculature |
| Toxicities | Toxicities |
|
|
