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. 2022 May 17;10(5):794. doi: 10.3390/vaccines10050794

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Analyses of IgG avidity to RBD in sera from heterologous or BNT-vaccinated individuals. Depicted are IgG avidity measurements for WT- and Delta-RBD binding from individuals vaccinated AZ/BNT/BNT (green) and BNT/BNT/BNT (orange) immunization schedules. Blood was collected at 0, 14, and 180 days post full vaccination and, additionally, 14 days after the booster immunization. Omicron-RBD avidity could not be determined, because it was below background values. Turquoise bars indicate the arithmetic mean for each group. Significance is indicated with two stars (**) for a p-value between 0.001 and 0.01.