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. 2022 May 17;10(5):794. doi: 10.3390/vaccines10050794

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Neutralization activity of sera from heterologous or BNT-immunized individuals. Sera from AZ/BNT/BNT (green) or BNT/BNT/BNT (orange) immunized individuals were analysed using lentiviral vectors pseudotyped with the WT, Delta, or Omicron spike protein. Neutralization is depicted as the reciprocal area under the curve. Blood was drawn at Days 0, 14, and 180 after full vaccination and, in addition, at Day 194, 14 days post booster vaccination. Turquoise bars indicate the arithmetic mean for each group. Significance is indicated with two stars (**) for a p-value between 0.001 and 0.01, and one star (*) denotes a p-value between 0.01 and 0.05.