Table 1.

Baseline characteristics of the population.

Features	Control	MCI	Dementia	p-Value
N (Male/Female)	115 (48/67)	71 (29/42)	65 (16/49)
Age (years)	71.9 ± 0.43	73.05 ± 0.54	75.1 ± 0.75	0.001
Education	9.12 ± 0.47	6.18 ± 0.57	3.56 ± 0.55	<0.001
MMSE	27.21 ± 0.2	24.96 ± 0.35	16.0 ± 0.73	<0.001
CDR	0.043 ± 0.01	0.26 ± 0.02	1.12 ± 0.09	<0.001
Total CHOL	195.6 ± 3.2	190.3 ± 4.1	201.4 ± 4.5	0.306
TG	137.4 ± 7.2	127.9 ± 7.7	152.6 ± 11.5	0.287
HDL	43.4 ± 0.89	43.1 ± 1.46	44.5 ± 1.2	0.371
LDL	124.7 ± 3.0	121.5 ± 3.4	126.4 ± 3.8	0.599
Platelet	253.3 ± 6.6	268.0 ± 7.2	266.2 ± 11.3	0.229
Glucose	101.4 ± 2.0	102.3 ± 2.5	107.5 ± 5.1	0.483
vitB12	790.6 ± 57.3	699.2 ± 31.6	717.1 ± 41.3	0.903
TIMP-3 (ng/mL)	0.61 ± 0.06	0.40 ± 0.04	0.39 ± 0.05 a	0.065

Values are mean ± SEM. MMSE, Mini-Mental State Examination; CDR, clinical dementia rating; SEM, standard error of the mean; Total CHOL, Total Cholesterol; TG, Triglycerides; HDL, High-density lipoprotein; LDL, Low-density lipoprotein; TIMP-3, Tissue inhibitor of metalloproteinase-3. p-values are for the Kruskal-Wallis test. Comparisons are assessed by Mann-Whitney U-tests. ^a Con: Dementia, p = 0.029.