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. 2022 May 19;10(5):803. doi: 10.3390/vaccines10050803

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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DC-SIGN expression in L. tarentolae-infected DCs. (A) DC-SIGN-specific mRNA expression was down-regulated upon internalization of Lt-wt. (B) The percentage of DC-SIGN expression following L. tarentolae infection was significantly reduced in DCs. DCs derived from healthy donors (n = 9). Box-plots show median, 25th and 75th percentiles, minimum and maximum values, while the symbol + indicates the mean value. Statistically significant differences at post-hoc tests are indicated; * p < 0.05; ** p < 0.01; *** p < 0.001. MED: untreated DCs.