. 2022 May 16;11(10):2794. doi: 10.3390/jcm11102794

Table 1.

Diagnostic and Statistical Manual of Mental Disorders (DSM-5) Female Sexual Dysfunction Disorders.

DSM-5 Female Sexual Dysfunction Disorders	Diagnosing Specific Female Sexual Dysfunction Disorders *	Other Conditions to Consider when Making Diagnoses of Specific Female Sexual Dysfunction Disorders
Female Orgasmic Disorder; 302.73 (F52.31)	Significant delay, infrequency, absence, or reduced intensity of orgasms in all/most sexual experiences with clinically significant distress over 6 months or more. Important additional considerations: - Barriers to orgasm are not due to lack of clitoral stimulation during vaginal penetration, a mental disorder, a medication/substance, history of abuse or interpersonal or sociocultural factors. - Consider whether an orgasm was experienced under any situation previously. - Diagnosis is based on subjective, self-reports from women.	1. Nonsexual mental disorders. 2. Substance/medication use. 3. Other medical condition. 4. Interpersonal factors. 5. Other sexual dysfunctions.
Female Sexual Interest/Arousal Disorder; 302.72 (F52.22)	Absent or markedly reduced sexual arousal or interest for at least 6 months with clinically significant distress as reflected by: 1. Lacking or low interest in sexual activity with reduced or no sexual or erotic thoughts. 2. Diminished openness to creating a sexual experience and/or being receptive to a partner’s sexual initiation. 3. Diminished or absent sexual arousal or pleasure during most or all sexual experiences. 4. Diminished or absent sexual responsivity to adequate intrapersonal, interpersonal, or external sexual cues. Additionally, sexual dysfunction is not better attributed to a mental disorder, relational distress, other life stressors, a medication/substance, history of abuse or interpersonal or sociocultural factors. Important additional considerations: - Desire discrepancy with a partner is not sufficient for diagnosis, although assessing for interpersonal contexts contributing to experience and symptoms is relevant to identifying etiology of distress or concerns. - With asexual self-identification, no diagnosis is made.	1. Nonsexual mental disorders. 2. Substance/medication use. 3. Other medical condition. 4. Interpersonal factors. 5. Other sexual dysfunctions. 6. Inadequate or absent sexual stimulation.
Genito-Pelvic Pain/Penetration Disorder; 302.76 (F52.6)	Experiencing difficulties with one or more of the following for at least 6 months with clinically significant distress: 1. Challenges to vaginal penetration during sexual activity. 2. Significant pain with attempted vaginal penetration. 3. Significant fear or anxiety about experiencing pain in anticipation of vaginal penetration, during or after vulvovaginal touch or attempted penetration. 4. Significant reflexive or involuntary muscular contraction of the pelvic floor muscles during attempted vaginal penetration.	1. Other medical condition (pelvic inflammatory disease, endometriosis, etc.) 2. Somatic symptom and related disorder. 3. Inadequate sexual stimulation.

DSM-5 Female Sexual Dysfunction Disorders

Diagnosing Specific Female Sexual Dysfunction Disorders *

Other Conditions to Consider when Making Diagnoses of Specific Female Sexual Dysfunction Disorders

Female Orgasmic Disorder; 302.73 (F52.31)

Significant delay, infrequency, absence, or reduced intensity of orgasms in all/most sexual experiences with clinically significant distress over 6 months or more.
Important additional considerations:

-
Barriers to orgasm are not due to lack of clitoral stimulation during vaginal penetration, a mental disorder, a medication/substance, history of abuse or interpersonal or sociocultural factors.
-
Consider whether an orgasm was experienced under any situation previously.
-
Diagnosis is based on subjective, self-reports from women.

1.
Nonsexual mental disorders.
2.
Substance/medication use.
3.
Other medical condition.
4.
Interpersonal factors.
5.
Other sexual dysfunctions.

Female Sexual Interest/Arousal Disorder; 302.72 (F52.22)

Absent or markedly reduced sexual arousal or interest for at least 6 months with clinically significant distress as reflected by:

1.
Lacking or low interest in sexual activity with reduced or no sexual or erotic thoughts.
2.
Diminished openness to creating a sexual experience and/or being receptive to a partner’s sexual initiation.
3.
Diminished or absent sexual arousal or pleasure during most or all sexual experiences.
4.
Diminished or absent sexual responsivity to adequate intrapersonal, interpersonal, or external sexual cues.

Additionally, sexual dysfunction is not better attributed to a mental disorder, relational distress, other life stressors, a medication/substance, history of abuse or interpersonal or sociocultural factors.
Important additional considerations:

-
Desire discrepancy with a partner is not sufficient for diagnosis, although assessing for interpersonal contexts contributing to experience and symptoms is relevant to identifying etiology of distress or concerns.
-
With asexual self-identification, no diagnosis is made.

1.
Nonsexual mental disorders.
2.
Substance/medication use.
3.
Other medical condition.
4.
Interpersonal factors.
5.
Other sexual dysfunctions.
6.
Inadequate or absent sexual stimulation.

Genito-Pelvic Pain/Penetration Disorder; 302.76 (F52.6)

Experiencing difficulties with one or more of the following for at least 6 months with clinically significant distress:

1.
Challenges to vaginal penetration during sexual activity.
2.
Significant pain with attempted vaginal penetration.
3.
Significant fear or anxiety about experiencing pain in anticipation of vaginal penetration, during or after vulvovaginal touch or attempted penetration.
4.
Significant reflexive or involuntary muscular contraction of the pelvic floor muscles during attempted vaginal penetration.

1.
Other medical condition (pelvic inflammatory disease, endometriosis, etc.)
2.
Somatic symptom and related disorder.
3.
Inadequate sexual stimulation.

* Specify: Lifelong or Acquired, Generalized or Situational, Mild/Moderate/Severe; for additional information, see the Fifth Edition of the Diagnostic and Statistical Manual.