Table 3.
Severe Disease in Non–COVID-19 Control Patients
| Code | Sex | Age, y | Primary Diagnoses | Outcome | Co-morbidities/thrombotic complications | Fibrinogen, mg/dL | AKI/dialysis | AST, U/L | ANC, /mm3 | LDH, U/L |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | M | 65 | CMMoL, ARDS | Discharged | Allogeneic stem cell transplant, AIHA, CMV viremia, parainfluenza pneumonia | 310 | – | 154 | 2.9 | 375 |
| 2 | F | 37 | HELLP syndrome | Discharged | C-section Gestational diabetes |
176 | +/No | 266 | 16.7 | 513 |
| 3 | F | 38 | ARDS | Discharged | Pneumonia, seizures | ND | +/No | 108 | 15.2 | 1574 |
| 4 | F | 56 | AML, ARDS | Died | Allogeneic stem cell transplant, cardiogenic shock, pneumonia, coronavirus infection (not CoV-1,2), DVT, PE | 391 | +/Yes | 88 | 14.3 | 977 |
| 5 | F | 81 | IgGκ multiple myeloma, ARDS | Died | DM2, pancreatitis, atrial fibrillation, influenza A pneumonia | 525 | +/No | 94 | 11.0 | 1555 |
| 6 | F | 45 | Angioimmunoblastic T-cell lymphoma | Died | Allogeneic stem cell transplant, Pseudomonas aeruginosa sepsis, HHV6 viremia, Coombs-negative hemolytic anemia, GvHD | ND | +/Yes | 33 | 2.0 | 1549 |
| 7 | F | 72 | r/o TTP | Discharged | HTN, HLD, atrial fibrillation/ischemic stroke | ND | – | 52 | 5.1 | ND |
| 8 | M | 76 | Cryptogenic cirrhosis | Discharged | Coombs-negative hemolytic anemia | ND | – | 87 | 1.6 | 1479 |
| 9 | M | 86 | Non-Hodgkin lymphoma, recurrent | Died | Sepsis, Coombs-negative hemolytic anemia | 311 | +/No | 264 | 0.3 | 2751 |
F, female; M, male; +, presence of acute kidney injury (AKI); –, absence of AKI; AIHA, autoimmune hemolytic anemia; AML, acute myelogenous leukemia; ANC, absolute neutrophil count; ARDS, acute respiratory distress syndrome; AST, aspartate transaminase; CMMoL, chronic myelomonocytic leukemia; CMV, cytomegalovirus; CoV-1,2, coronavirus 1,2; COVID-19, coronavirus disease 2019; DM2, type 2 diabetes mellitus; DVT, deep vein thrombosis; GvHD, graft-versus-host disease; HELLP, hemolysis/elevated liver enzymes/low platelets; HHV6, human herpesvirus 6; HLD, hyperlipidemia; HTN, hypertension; LDH, lactate dehydrogenase; ND, not done; PE, pulmonary embolism; r/o, rule out; TTP, thrombotic thrombocytopenic purpura.