TABLE 1.

The apparent dissociation constant (K _d ) values for defensin‐based ACE2 mimetic binding into SARS‐CoV‐2 Spike protein

ACE2‐defensin	K d (nM)
h‐deface2	54.4 ± 11.3
p‐deface2	33.5 ± 8.2
p‐deface‐MUT	14.4 ± 3.5
p‐deface‐ala	N/A

Note: Apparent K _d values were determined using ELISA dose–response assays using variable ACE2 mimetic concentrations and nonlinear regression Michaelis‐Menten curve fits. Measurements were performed in triplicates and errors correspond to standard deviation.