Table 1.

In vivo Antitumor Effect of Free Photosensitizer and MOFs-Based PDT

Free Photosensitizer	TGI (Tumor Growth Inhibition) Value	MOFs-Based PDT	TGI Value	Ref
5,15-di (p-benzoato) porphyrin (H2DBP)	−25%	DBP-UiO	98%	[47]
5,15-di (p-benzoato) chlorin (H2DBC)	17% in CT26 models; 14% in HT29 models	DBC-UiO	88% in CT26 models; 68% in HT29 models	[52]
5,10,15,20-tetra (p-benzoate) porphyrin (H4TBP)	33%	Ti-TBP	98%	[53]
5,10,15,20-tetra (p-benzoate) bacteriochlorin (H4TBB)	43% in 4T1 models; 57% in MC38 models	Zr-TBB	94% in 4T1 models; 99% in MC38 models	[54]
H2BDC	9%	TMPyP4-G4-aptamer-NMOFs	95%	[55]
Ce6	49%	Ce6@ZIF-8	94%	[56]
Ce6	50%	MCOPP-NE-Ce6	90%	[57]