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. 2022 May 16;14(5):1066. doi: 10.3390/pharmaceutics14051066

Table 4.

Current mRNA COVID-19 vaccine Stability profile, dose, and dosing schedule.

Stability Profile Manufacturer References
Moderna Pfizer-BioNTech
Frozen State −20 °C up to 6 months −80 °C to −60 °C up to 6 months [78,89,109,166,167,168]
2–8 °C 30 days Up to 5 days
Room Temperature Up to 12 h. Up to 2 h. (up to 6 h. after dilution)
Dose 100 µg (0.5 mL) 30 µg (0.3 mL) [109,159,169]
Dosing Schedule Day 1, Day 29 Day 1, Day 21