Table 1.
Baseline characteristic of participants with or without MAFLD in NHANES 2017–2018
| Non-MALFD (n = 2029) | MAFLD (n = 2604) | ||||
|---|---|---|---|---|---|
| Wholea | Mild (n = 429) | Moderate (n = 326) | Severe (n = 1849) | ||
| Age (year) | 42.0 (33) | 55.0 (25) | 56.0 (25) | 53.5 (30) | 55.0 (24) |
| Gender | |||||
| Male | 903 (44.5) | 1378 (52.9) | 189 (44.1) | 161 (49.4) | 1028 (55.6) |
| Female | 1126 (55.5) | 1226 (47.1) | 240 (55.9) | 165 (50.6) | 821 (44.4) |
| Race-ethnicity | |||||
| Mexican American | 204 (10.0) | 451 (17.3) | 53 (12.4) | 42 (12.9) | 356 (19.3) |
| Other Hispanic | 174 (8.6) | 263 (10.1) | 56 (13.1) | 32 (9.8) | 175 (9.5) |
| Non-Hispanic White | 714 (35.2) | 892 (34.3) | 121 (28.2) | 120 (36.8) | 651 (35.2) |
| Non-HISPANIC Black | 512 (25.2) | 521 (20.0) | 108 (25.2) | 70 (21.5) | 343 (18.6) |
| Other Race | 425 (20.9) | 477 (18.3) | 91 (21.2) | 62 (19.0) | 324 (17.5) |
| BMI (kg/m2) | 24.6 (6.1) | 31.5 (8.3) | 29.2 (7.15) | 29.4 (6.825) | 32.4 (8.7)cd |
| WC (cm) | 87.8 (17.3) | 106.5 (20.0) | 101.0 (16.0) | 101.9 (15.9) | 109.4 (20.5)cd |
| HC (cm) | 97.85 (12.8) | 109.0 (17.7) | 105.6 (16.5) | 106.4 (15.3) | 110.4 (18.3)cd |
| ALT (IU/L) | 15.0 (9) | 20.0 (15) | 17.0 (10) | 19.0 (12)b | 22.0 (16)cd |
| AST (IU/L) | 19.0 (7) | 20.0 (9) | 19.0 (8) | 19.0 (8) | 20.0 (10)c |
| GGT (IU/L) | 17.0 (13) | 25.0 (21) | 20.0 (15) | 23.0 (18) | 26.0 (24)cd |
| ALB (g/L) | 41.0 (4) | 41.0 (5) | 40.0 (4) | 40.0 (4) | 41.0 (5) |
| Cholesterol (mmol/L) | 4.63 (1.33) | 4.88 (1.42) | 4.86 (1.36) | 4.84 (1.3) | 4.89 (1.42) |
| Triglyceride (mg/dL) | 91.0 (63) | 139.0 (99) | 118.0 (76) | 125.0 (96) | 147.0 (102)cd |
| HDLC (mmol/L) | 1.45 (0.49) | 1.22 (0.42) | 1.29 (0.46) | 1.24 (0.49) | 1.16 (0.39)cd |
| Hs-CRP (mg/L) | 1.14 (2.11) | 2.62 (4.1) | 2.05 (3.52) | 2.07 (3.01) | 2.87 (4.29)cd |
| Fasting Glucose (mmol/L) | 5.00 (0.67) | 5.38 (1.11) | 5.27 (0.75) | 5.27 (0.95) | 5.44 (1.27)cd |
| HbA1c (%) | 5.4 (0.5) | 5.7 (0.8) | 5.6 (0.7) | 5.6 (0.7) | 5.8 (1.0)cd |
| Insulin (μU/mL) | 6.96 (5.62) | 13.2 (12.6) | 10.08 (6.53) | 10.17 (9.25) | 15.09 (13.7)cd |
| Liver stiffness | 4.5 (1.8) | 5.4 (2.4) | 4.9 (2.0) | 5.1 (2.0) | 5.6 (2.7)cd |
| CAP (dB/m) | 213 (43) | 303 (62) | 258.0 (10) | 273.0 (6) | 321.0 (52) |
BMI body mass index, WC waist circumference, HC hip circumference, ALT alanine aminotransferase, AST aspartate aminotransferase, GGT aamma glutamyltransferase, ALB albumin, HDLC high density lipoprotein cholesterol, CAP controlled attenuation parameter
aAll the indexes between Non-MAFLD and MAFLD have statistical differences (P < 0.05)
bThere are statistical difference between mild and moderate MAFLD groups (P < 0.05)
cThere are statistical difference between mild and severe MAFLD groups (P < 0.05)
dThere are statistical difference between moderate and severe MAFLD groups (P < 0.05)