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Apoptosis caused by U87-Selu exo in U87MG cells. (a) Western blot of U87MG cells treated with U87-Selu exo and selumetinib. (b) p27 expression levels at 12, 24, and 48 h. (c) PCNA expression levels at 12, 24, and 48 h. (d) Cyclin D1 expression levels at 12, 24, and 48 h. (e) p-p38 expression levels at 12, 24, and 48 h. * p < 0.05, ** p < 0.01, *** p < 0.001 vs. non-treated control for each time point; # p < 0.05, ## p < 0.01 vs. U87-Selu exo. n = 3.
