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Concentrations inducing a 10% loss of viability (10% Effective Dose, or ED10, including a 90% Confidence Interval (CI)), calculated by dose–response modelling. For nanostars, an ED10 could not be calculated. The data of the three replicate experiments were analysed together.
| Nanospheres | Nanorods | |||
|---|---|---|---|---|
| ED10 (µg/mL) | 90% CI | ED10 (µg/mL) | 90% CI | |
| Wildtype | 9.5 | 2.4–18.0 | 34.1 | 20.4–51.8 |
| ASC-def | 12 | 6.8–17.1 | 169 | 97.2–299 |
| NLRP3-def | 17.7 | 10.7–18.5 | 166 | 47.7–242 |
