Table 1.
Effects of bisphenol A (BPA) on the growth characteristics of mice administered a high-fat/high-cholesterol/high-cholic-acid diet (HFCCD).
| ND | HFCCD | BPA + HFCCD | NAC + BPA + HFCCD | |
|---|---|---|---|---|
| Initial body wt (g) | 24.0 ± 1.3 | 23.6 ± 0.6 | 24.0 ± 1.7 | 24.0 ± 0.5 |
| Body wt after 4 weeks of the HFCCD diet (g) | 27.2 ± 1.2 b | 27.2 ± 0.9 b | 29.5 ± 1.8 a | 26.2 ± 0.5 b |
| Final body wt (g) | 28.7 ± 2 b | 28.8 ± 1.3 b | 25.9 ± 0.4 a | 28.1 ± 1.6 b |
| Liver wt (g) | 1.046 ± 0.027 c | 1.301 ± 0.073 b | 1.549 ± 0.135 a | 1.403 ± 0.091 b |
| Liver wt/ body wt (%) |
3.665 ± 0.239 c | 4.539 ± 0.416 b | 6.004 ± 0.434 a | 4.997 ± 0.224 b |
| Spleen wt (g) | 0.077 ± 0.006 c | 0.099 ± 0.005 b | 0.117 ± 0.002 a | 0.098 ± 0.010 b |
| Spleen wt/ body wt (%) |
0.268 ± 0.023 c | 0.346 ± 0.028 b | 0.452 ± 0.016 a | 0.350 ± 0.052 b |
| Epididymal fat wt (g) | 0.751 ± 0.089 | 0.795 ± 0.075 | 0.864 ± 0.271 | 0.662 ± 0.091 |
| Epididymal fat wt/ body wt (%) |
2.646 ± 0.464 | 2.761 ± 0.178 | 3.353 ± 1.062 | 2.351 ± 0.239 |
| Brown fat wt (g) | 0.119 ± 0.019 a | 0.112 ± 0.009 a | 0.078 ± 0.016 b | 0.108 ± 0.009 a |
| Brown fat wt/ body wt (%) |
0.415 ± 0.065 a | 0.390 ± 0.028 a | 0.302 ± 0.028 b | 0.381 ± 0.072 a |
Data are presented as the mean ± SD; a,b,c p < 0.05.