Table 2.

Biomarker combinations. (+) means high expression and (−) means lack of expression of a protein at a certain location.

Cell Type	Biomarker Combination
Helper T cells ($T_h$)	Epcam(−) CD45(+) CD3(+) CD4(+) CD8(−)
Cytotoxic T cells ($T_C$)	Epcam(−) CD45(+) CD3(+) CD4(−) CD8(+)
Naive dendritic cells ($D_N$)	Epcam(−) CD45(+) F4/80(−) CD11C(+)
Dendritic cells (D)	Epcam(−) CD45(+) F4/80(−) CD11C(+) MHC-II(+)
Activated macrophages (M)	Epcam(−) CD45(+) F4/80(+) CD11C(−) CSF1R(+) or Epcam(−) CD45(+) F4/80(+) CD11C(−) CSF1R(−) MHC-II(+)
Cancer cells (C)	Epcam(+) CD45(−)
Necrotic cells (N)	CC3(+)