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Neutralization of SARS-CoV-2 by plant-made CA1 and CB6. Serially diluted plant-made CA1 (A) or CB6 (B) were mixed with SARS-CoV-2 before adding to Vero E6 cells in a 96-well plate for 24 h. Cells were fixed, permeabilized, and stained for SARS-CoV-2 S protein. Foci were quantified, percent neutralization was calculated, and IC50 was determined. Error bars represent SD and at least two independent experiments were performed with technical triplicates.
