Figure 3.

Mutational profile in alveolar soft part sarcoma, with recurrent mutations identified in 34 cases. (A) Cancer consensus genes altered by nonsynonymous mutations in at least 3 of 34 patients with alveolar soft part sarcoma. The y-axis represents the number of cases with nonsynonymous mutations, and the x-axis represents mutated genes. The number of predictively pathogenic events is coded in grayscale. The lollipop plots mapped the mutations in (B) PDE4DIP and (C) ALK on the linear protein sequence and their domains (colored boxes). The Y-axis represents the number of cases with mutations, The x-axis represents the amino acid sequence of mutated genes, and aa stands for amino acids.