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The role of methyl-group donors nutrients in DNA methylation. DHF: dihydrofolate; THF: tetrahydrofolate; B6: vitamin B6; B2: vitamin B2; B12: vitamin B12; DHFR: dihydrofolate reductase; 5-10′ MTHF: 5, 10-methylene tetrahydrofolate; MTHFR: methylenetetrahydrofolate reductase; 5′ MTHF: 5-methyl tetrahydrofolate; SAM: S-adenosylmethionine; SAH: S-adenosylhomocysteine.
