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. 2022 Apr 22;15(5):514. doi: 10.3390/ph15050514

Table 5.

Antibacterial activity of QACs with different alcohols against biofilms.

Compositions MIC/MBC (mg/L)
Reference Strains Clinical Strains
Sa Ec Kp Ab Pa Sa Ec Kp Ab Pa
PhE 1: n = 9, Br 2 8 16 250 63 4 4 63 125 63
2 16 32 250 63 4 4 63 125 125
PhE 2: n = 10, Br 1 4 32 63 32 4 8 63 32 32
2 16 63 250 63 4 16 63 125 250
PhE 3: n = 10, Br 2 16 16 125 63 4 1 63 32 32
2 32 63 500 250 8 16 125 125 125
PhE BAC 16 16 32 32 125 8 16 32 32 63
16 16 32 32 125 32 16 32 32 125
PhE OCT 1 4 8 16 16 2 4 16 16 16
4 8 16 32 63 4 16 32 32 32
PhE/H2O (control) 32 16 63 63 125 63 32 63 63 32
63 32 125 250 125 125 63 125 125 125
IPA 1: n = 9, Br 2 4 8 32 16 2 4 8 32 16
8 4 8 63 32 8 4 8 63 32
IPA 2: n = 10, Br 4 4 16 32 16 4 4 16 16 32
8 4 32 32 32 8 4 63 32 32
IPA 3: n = 10, Br 2 4 8 32 16 1 4 16 16 16
4 4 16 32 32 2 4 32 16 63
IPA BAC 16 16 32 32 125 16 16 32 32 63
16 16 32 32 125 32 16 32 32 125
IPA OCT 2 4 4 16 8 2 4 16 16 16
2 8 8 32 32 4 4 32 32 32
IPA/H2O (control) 32 16 63 63 125 63 32 63 63 32
63 32 63 250 125 125 63 125 250 125
IPAP 1: n = 9, Br 1 4 8 32 16 2 1 16 32 16
2 4 16 63 63 4 4 32 32 63
IPAP 2: n = 10, Br 1 8 16 32 32 2 8 32 32 32
2 32 63 125 63 4 8 63 63 125
IPAP 3: n = 10, Br 4 16 16 32 16 2 2 32 32 16
4 16 16 63 63 4 4 32 63 63
IPAP BAC 16 1 32 32 125 16 1 32 32 63
16 2 32 63 250 32 8 32 32 500
IPAP OCT 1 2 8 8 16 2 2 16 16 16
4 4 8 16 63 4 8 16 32 125
IPAP/H2O (control) 32 16 63 63 125 32 32 63 63 32
63 32 63 125 125 125 63 125 125 125

Note: color indicates results that do not differ (or worse) from those of individual substances or control samples, i.e., formulation is not effective.