Table 4.

Microbiological activity of some TZD derivatives on clinical strains of Candida spp fungi; n.d.—no data. Flc = fluconazole.

Microorganism	MIC (µg/mL)
	Flc	2		5a		7a		12e
		24 h	48 h	24 h	48 h	24 h	48 h	24 h	48 h
C. parapsilosis ATCC 22019	4	16	32	16	32	32	64	<0.125	0.5
C. albicans ATCC 24433	4	8	16	8	16	8	32	0.125	0.25
C. tropicalis 3019	2	32	64	32	32	64	64	64	64
C. kefyr 77	n.d.	8	16	8	16	16	32	64	64
C. famata 312	n.d.	32	64	32	32	64	>64	>64	>64
C. guilliermondii 355	n.d.	64	64	n.d.	n.d.	64	64	64	64
C. parapsilosis 58N	n.d.	64	64	n.d.	n.d.	64	64	>64	>64
C. krusei 432M	>32	16	32	16	16	32	64	64	64
C. glabrata 61L	32	8	16	8	16	16	32	64	64
C. albicans 604M	>32	32	64	32	32	64	64	>64	>64