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. 2022 May 19;23(10):5690. doi: 10.3390/ijms23105690

Figure 6.

Figure 6

Circular dichroism (CD) spectra of the 22AG quadruplex in the absence (black spectra) and in the presence (red spectra) of berberine (22AG:Berb = 1:10) in (A) 30 mM Tris, 100 mM NaCl, pH 7.4, and (B) 30 mM Tris, 100 mM KCl, pH 7.4. In the bottom panels, the CD spectra for the RG-1 sequence in the absence (black spectra) and in the presence (red spectra) of berberine (22AG:Berb = 1:10) are reported for the measurements carried out in (C) 30 mM Tris, 100 mM NaCl, pH 7.4, and (D) 30 mM Tris, 100 mM KCl, pH 7.4. The path length of the cuvette was 0.1 cm. The temperature was set to 25 °C.