AD	Alzheimer’s disease
APOE	Apolipoprotein E
CO	Centenarian offspring
CVDs	Cardiovascular diseases
FOXO3	Forkhead box O3
GWAS	Genome-wide association study
HAP	Healthy aging phenotype
IGF	Insulin growth factor
LLF	Long-life family
LLIs	Long-lived individuals
LMNA	Lamin A/C
MedDiet	Mediterranean diet
NGS	Next generation sequencing
OR	Odd ratio
SIRT6	Sirtuin 6
SNP	Single nucleotide polymorphism
US	United States
WHO	World Health Organization