Table 3.

Pharmacological strategies determining IOP reduction in STP.

Author—Year	Drug Administered	Results
Agrawal et al. [59]—2013	Propofol/thiopentone for induction and propofol/1% isoflurane for maintenance	Induction and maintenance with propofol TIVA is the best option as induction with propofol decreased IOP by almost 50%
Molloy et al. [61]—2014	Dorzolamide-timolol when IOP exceeded 40 mmHg	IOP reduction
Molloy et al. [58]—2016	Dorzolamide-timolol after induction of anaesthesia and when IOP exceeded 40 mmHg	IOP reduction
Kaur et al. [37]—2018	Anaesthesia using intravenous propofol/sevoflurane	IOP is significantly greater (p < 0.01) in patients treated with sevoflurane compared with those treated with propofol.
Kitamura et al. [60]—2018	Dexmetomidine	Dexmedetomidine combined with propofol decreases IOP in the steep Trendelenburg position during RALP
Mathew et al. [62]—2018	Brimonidine tartrate 1% preoperatively	No significant differences with placebo

Abbreviations: IOP (intraocular pressure); robot-assisted laparoscopic prostatectomy (RALP); Totally Intravenous Anaesthesia (TIVA).