Figure 6.

Correlation between [¹⁸F]THK5351 or [¹⁸F]MK6240 uptake and [¹⁸F]Flutemetamol uptake in brain. (A) The correlation between [¹⁸F]THK5351 uptake and [¹⁸F]Flutemetamol uptake were assessed in the cerebral cortex and hippocampus of 6 × Tg mice by the nonparametric Spearman’s rank correlation test. Graphs show regression lines with 95% confidence intervals. [¹⁸F]THK5351 uptake significantly correlates with [¹⁸F]Flutemetamol uptake both in the cortex and hippocampus of 6 × Tg mice. (B) The correlation between [¹⁸F]MK6240 uptake and [¹⁸F]Flutemetamol uptake are assessed in the cortex and hippocampus of 6 × Tg mice by the nonparametric Spearman’s rank correlation test. Graphs show regression lines with 95% confidence intervals. [¹⁸F]MK6240 uptake significantly correlates with [¹⁸F]Flutemetamol uptake both in the cortex and hippocampus of 6xFAD mice.