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. 2022 Apr 22;15(5):517. doi: 10.3390/ph15050517

Table 1.

Baseline characteristics of esophageal cancer participants after propensity score overlap weighting adjustment.

Characteristics After PS Overlap Weighting Adjustment After PS Overlap Weighting Adjustment in Esophageal Cancer Pts
Esophageal Cancer Control SMD Deceased pts Survived pts SMD
Total participants (n, %) 811 (100) 3244 (100) 341 (100) 470 (100)
Age, % 0.00 0.00
40–44 0.21 0.21 0.10 0.10
45–49 1.54 1.54 1.47 1.47
50–54 6.25 6.25 6.51 6.51
55–59 10.90 10.90 11.59 11.59
60–64 15.43 15.43 15.94 15.94
65–69 22.77 22.77 22.12 22.12
70–74 20.56 20.56 20.90 20.90
75–79 15.14 15.14 14.52 14.52
80–84 5.59 5.59 5.21 5.21
85+ 1.60 1.60 1.64 1.64
Sex, % 0.00 0.00
Male 92.98 92.98 93.46 93.46
Female 7.02 7.02 6.54 6.54
Income, % 0.00 0.00
1 (lowest) 16.94 16.94 16.71 16.71
2 14.10 14.10 12.56 12.56
3 16.13 16.13 17.27 17.27
4 21.92 21.92 23.55 23.55
5 (highest) 30.92 30.92 29.91 29.91
Region of residence, % 0.00 0.00
Urban 38.42 38.42 39.55 39.55
Rural 61.58 61.58 60.45 60.45
Obesity †, % 0.00 0.00
Underweight 5.82 5.82 5.95 5.95
Normal 46.86 46.86 51.63 51.63
Overweight 25.34 25.34 23.80 23.80
Obese I 21.00 21.00 18.02 18.02
Obese II 0.98 0.98 0.60 0.60
Smoking status, % 0.00 0.00
Nonsmoker 42.92 42.92 38.91 38.91
Past smoker 22.50 22.50 21.92 21.92
Current smoker 34.58 34.58 39.17 39.17
Alcohol consumption, % 0.00 0.00
<1 time a week 46.71 46.71 42.65 42.65
≥1 time a week 53.29 53.29 57.35 57.35 0.00
SBP (Mean, SD) 129.53 (14.48) 129.53 (6.73) 0.00 129.41 (10.10) 129.41 (12.64) 0.00
DBP (Mean, SD) 78.79 (8.57) 78.79 (4.18) 0.00 78.72 (5.75) 78.72 (7.78) 0.00
Fasting blood glucose (Mean, SD) 104.48 (22.57) 104.48 (12.57) 0.00 104.23 (15.74) 104.23 (19.57) 0.00
Total cholesterol (Mean, SD) 188.18 (30.98) 188.18 (14.88) 0.00 185.96 (21.90) 185.96 (26.55) 0.00
CCI score (Mean, SD) 2.38 (1.93) 2.38 (1.05) 0.00 3.14 (1.51) 3.14 (1.79) 0.00
GERD episodes for 1 year before index date (Mean, SD) 0.93 (1.48) 0.93 (1.12) 0.00 1.27 (1.38) 1.27 (1.50) 0.00
Treatment type, % 0.00
No records of treatment - - 34.65 34.65
Surgery only - - 16.04 16.04
Surgery + RT or CT - - 49.31 49.31

Abbreviations: PS—propensity score; SMD—standardized mean difference; pts—patients; CCI—Charlson Comorbidity Index; SBP—systolic blood pressure; DBP—diastolic blood pressure; SD—standard deviation; GERD—gastroesophageal reflux disease; CT—chemotherapy; RT—radiotherapy. † Obesity (BMI—body mass index, kg/m2) was categorized as <18.5 (underweight), ≥18.5 to <23 (normal), ≥23 to <25 (overweight), ≥25 to <30 (obese I), and ≥30 (obese II).