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Inhibition mode of L-CDP1, L-CDP7, and L-CDP8 over SARS-CoV-2 3CLpro. Lineweaver-Burk plots to determine the inhibition modes are presented. [S] is the substrate concentration; v is the initial reaction rate. (A): Lineweaver-Burk plot for L-CDP1 inhibition of SARS-CoV-2 3CLpro. (B): Lineweaver-Burk plot for L-CDP7 inhibition of SARS-CoV-2 3CLpro. (C): Lineweaver-Burk plot for L-CDP8 inhibition of SARS-CoV-2 3CLpro. Data shown are the mean ± SD from 3 independent measurements (n = 3).
