Table 3.

Univariate and multivariate logistic regression analyses of the factors associated with poor COVID-19 outcome in HIV-positive patients.

Factor		Univariate			Multivariate
		Odds Ratio	95% Confidence Interval	p-Value	Odds Ratio	95% Confidence Interval	p-Value
Demographics	Age [unit = 10]	1.17	0.85–1.62	0.3296	-	-	-
	BMI [unit = 1]	0.98	0.91–1.06	0.6678	-	-	-
	Male sex	0.82	0.36–1.87	0.6428	-	-	-
	Currently employed	0.31	0.13–0.7	0.0051	0.46	0.18–1.22	0.1201
Comorbidities	Always smoked cigarettes	1.46	0.63–3.97	0.3816	-	-	-
	One or more comorbidities	2.73	1.22–6.13	0.0148	2.52	1–6.3	0.0490
	Number of comorbidities [unit = 1]	2.33	1.43–3.8	0.0007	2.12	1.2–3.7	0.0091
	HCV and/or HBV co-infection	3.17	1.32–7.60	0.0097	1.51	0.5–4.5	0.4636
	mode of HIV infection
HIV characteristics	heterosexual vs. MSM	0.65	0.26–1.64	0.8786	-	-	-
	IDU vs. MSM	0.81	0.26–2.6		-	-	-
	Other vs. MSM	1.3	0.131–12.88		-	-	-
	Unknown vs. MSM	0.52	0.06–4.53		-	-	-
	Time since HIV diagnosis in years [unit = 1]	1	0.94–1.06	0.9932	-	-	-
	CD4 count [unit = 100]	0.86	0.8–1	0.0225	0.92	0.8–1.1	0.2134
	HIV VL > = 50 copies/mL	1.91	0.8–4.56	0.1461	-	-	-
	On cART	0.23	0.08–0.63	0.0044	0.2	0.05–0.8	0.0231
	Third drug in cART
	InSTI vs. PI	0.46	0.17–1.25	0.2523	-	-	-
	NNRTI vs. PI	0.15	0.02–1.34		-	-	-
	Other vs. PI	0.8	0.08–7.99		-	-	-
	No TDF or TAF in backbone	1.73	0.78–3.87	0.1793	-	-	-
COVID-19 characteristics	Any COVID-19 symptoms	0.74	0.15–3.56	0.7055	-	-	-
	typical radiological changes	3.9	1.12–13.65	0.0124	4.23	1.06–16.99	0.0418
	non-typical radiological changes	10.8	2.23–52.5	0.0124	6.39	1.02–39.72	0.0465