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JAK3 (pdb: 5TOZ) bound to ritlecitinib: (A) 3D representation of JAK3 bound to ritlecitinib (shown as CPK); (B) 3D binding mode of ritlecitinib showing one covalent bond with Cys909, hydrogen bonds (shown as green-dotted lines), and multiple hydrophobic interactions, this figure was generated using Discovery Studio Visualizer (V16.1.0.15350).
