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Binding modes of ruxolitinib (shown as sticks) into human JAK2 JH1 (pdb: 6WTN): (A) 3D binding mode, receptor shown as a hydrogen bond surface; (B) 2D binding mode showing different types of interactions with JAK2 JH1; hydrogen atoms were omitted for clarity; this figure was generated using Discovery Studio Visualizer (V16.1.0.15350).
