Figure 64.
Binding modes of tofacitinib (shown as sticks) into the PRK1 catalytic domain (pdb: 4OTI): (A) 3D binding mode, receptor shown as a hydrogen bond surface; (B) 2D binding mode showing different types of interactions with PRK1 catalytic domain; hydrogen atoms were omitted for clarity; this figure was generated using Discovery Studio Visualizer (V16.1.0.15350).
