Table 4.

The gender differences in tissue responses with different CBD doses.

Dose	Tissue CBD Concentration (mg/kg)
	Adipose		Muscle		Liver a
	Female	Male	Female	Male	Female	Male
Low (30 mg/kg/day)	7.79 ± 7.29	2.79 ± 1.20	0.04 ± 0.02	0.50 ± 0.47	0.09 ± 0.03 *	0.05 ± 0.02
Medium (115 mg/kg/day)	197.01 ± 101.52 *	35.31 ± 21.01	0.85 ± 0.22 **	0.43 ± 0.11	1.59 ± 0.31 **,b	0.30 ± 0.04 b
High (230 mg/kg/day)	84.24 ± 32.97	132.95 ± 106.74	1.25 ± 0.20 **	0.60 ± 0.11 *	1.94 ± 0.60 **	0.37 ± 0.07

Data are means ± SEM; ^a p < 0.05 group difference between males and females * p < 0.05 and ** p < 0.01 relative to control; ^b p < 0.01 dose specific difference between genders.