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. 2022 May 19;27(10):3265. doi: 10.3390/molecules27103265

Table 4.

Protein tyrosine phosphatase 1B inhibitory results of S,S,R-5.

Samples Mol wt. Conc (μM/mL) Percent Inhibition IC50 (μM)
S,S,R-5 384 500
250
125
62.5
31.25
88.35 ± 0.89 ns
84.36 ± 1.15 ns
79.62 ± 0.03 ns
76.16 ± 0.12 ns
73.67 ± 0.35 ns
0.91 ± 0.10
Ursolic acid 457 500
250
125
62.5
31.25
90.83 ± 0.47
87.23 ± 0.96
82.29 ± 0.57
78.33 ± 0.55
76.03 ± 0.77
1.35 ± 0.13

Data was expressed as mean percent inhibition ± SEM. Two-way ANOVA followed by Bonferroni’s posttest was used for statistical analysis. ns; not significant compared to that of the standard drugs.