Table 2.
Control | HDPs | GH | PE | SPE | |||||
---|---|---|---|---|---|---|---|---|---|
(n = 254) | (n = 196) | (n = 78) | (n = 106) | (n = 12) | |||||
p-Values | p-Values | p-Values | p-Values | ||||||
Age at delivery (years) | 31.2 ± 6.7 | 31.8 ± 6.3 | 0.388 | 32.1 ± 6.2 | 0.354 | 31.2 ± 6.3 | 0.985 | 35.3 ± 6.1 | 0.036 * |
Proportion of primigravidae (%) | 63.1 | 58.2 | 0.387 | 54.1 | 0.312 | 59.8 | 0.608 | 58.3 | 0.744 |
Family history of hypertension (%) | 23.1 | 35.9 | 0.01 * | 30.2 | 0.324 | 36.4 | 0.02 * | 54.5 | 0.019 * |
History of HDPs (%) | 0.0 | 31.0 | <0.001 * | 30.4 | <0.001 * | 32.7 | <0.001 * | 22.2 | <0.001 * |
Hypertension (%) | 1.45 | 7.78 | 0.003 * | 0.0 | 0.392 | 1.89 | 0.77 | 91.7 | <0.001 * |
Diabetes mellitus (%) | 0.48 | 0.0 | 0.368 | 0.0 | 0.622 | 0.0 | 0.474 | 0.0 | 0.809 |
Renal disease (%) | 0.97 | 2.99 | 0.15 | 2 | 0.541 | 3.77 | 0.087 | 0.0 | 0.732 |
Autoimmune disease (%) | 1.45 | 0.0 | 0.118 | 0.0 | 0.392 | 0.0 | 0.213 | 0.0 | 0.675 |
Systolic blood pressure (mmHg) | 118.4 ± 17.5 | 163.8 ± 22.8 | <0.001 * | 148.8 ± 18.2 | <0.001 * | 168.9 ± 21.2 | <0.001 * | 183.1 ± 20.4 | <0.001 * |
Diastolic blood pressure (mmHg) | 73.4 ± 11.7 | 98.8 ± 17.4 | <0.001 * | 90.3 ± 16.3 | <0.001 * | 101.2 ± 16.8 | <0.001 * | 112.7 ± 11.3 | <0.001 * |
BMI before pregnancy (kg/m2) | 20.7 ± 3.0 | 23.2 ± 4.8 | <0.001 * | 22.8 ± 3.9 | 0.001 * | 23.0 ± 4.7 | <0.001 * | 26.5 ± 7.4 | 0.019 * |
BMI at delivery (kg/m2) | 24.8 ± 2.7 | 26.9 ± 4.3 | <0.001 * | 26.8 ± 3.8 | 0.002 * | 26.6 ± 4.1 | <0.001 * | 29.3 ± 7.2 | 0.052 |
Body weight gained during pregnancy (kg) | 10.2 ± 4.2 | 9.4 ± 6.2 | 0.231 | 9.8 ± 6.0 | 0.694 | 9.6 ± 6.5 | 0.423 | 7.1 ± 5.3 | 0.019 * |
Gestational age at delivery (weeks) | 38.7 ± 1.7 | 35.1 ± 4.0 | <0.001 * | 37.0 ± 2.7 | <0.001 * | 34.4 ± 4.1 | <0.001 * | 33.0 ± 5.5 | 0.004 * |
Birth weight of the neonate (g) | 3042.5 ± 479.7 | 2150.8 ± 863.9 | <0.001 * | 2565.5 ± 692.6 | <0.001 * | 1997.8 ± 833.1 | <0.001 * | 1835.9 ± 1156.0 | 0.003 * |
Apgar score at 5 min | 8.7 ± 0.8 | 7.7 ± 2.3 | <0.001 * | 8.5 ± 1.0 | 0.408 | 7.4 ± 2.5 | <0.001 * | 6.5 ± 3.0 | 0.027 * |
Values of the continuous variables are expressed as the means ± standard deviation. HDPs: hypertensive disorders of pregnancy; GH: gestational hypertension; PE: pre-eclampsia; SPE: superimposed pre-eclampsia; BMI: body mass index. * p < 0.05.