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. 2022 Apr 26;58(5):591. doi: 10.3390/medicina58050591

Table 2.

Characteristics of the study participants.

Control HDPs GH PE SPE
(n = 254) (n = 196) (n = 78) (n = 106) (n = 12)
p-Values p-Values p-Values p-Values
Age at delivery (years) 31.2 ± 6.7 31.8 ± 6.3 0.388 32.1 ± 6.2 0.354 31.2 ± 6.3 0.985 35.3 ± 6.1 0.036 *
Proportion of primigravidae (%) 63.1 58.2 0.387 54.1 0.312 59.8 0.608 58.3 0.744
Family history of hypertension (%) 23.1 35.9 0.01 * 30.2 0.324 36.4 0.02 * 54.5 0.019 *
History of HDPs (%) 0.0 31.0 <0.001 * 30.4 <0.001 * 32.7 <0.001 * 22.2 <0.001 *
Hypertension (%) 1.45 7.78 0.003 * 0.0 0.392 1.89 0.77 91.7 <0.001 *
Diabetes mellitus (%) 0.48 0.0 0.368 0.0 0.622 0.0 0.474 0.0 0.809
Renal disease (%) 0.97 2.99 0.15 2 0.541 3.77 0.087 0.0 0.732
Autoimmune disease (%) 1.45 0.0 0.118 0.0 0.392 0.0 0.213 0.0 0.675
Systolic blood pressure (mmHg) 118.4 ± 17.5 163.8 ± 22.8 <0.001 * 148.8 ± 18.2 <0.001 * 168.9 ± 21.2 <0.001 * 183.1 ± 20.4 <0.001 *
Diastolic blood pressure (mmHg) 73.4 ± 11.7 98.8 ± 17.4 <0.001 * 90.3 ± 16.3 <0.001 * 101.2 ± 16.8 <0.001 * 112.7 ± 11.3 <0.001 *
BMI before pregnancy (kg/m2) 20.7 ± 3.0 23.2 ± 4.8 <0.001 * 22.8 ± 3.9 0.001 * 23.0 ± 4.7 <0.001 * 26.5 ± 7.4 0.019 *
BMI at delivery (kg/m2) 24.8 ± 2.7 26.9 ± 4.3 <0.001 * 26.8 ± 3.8 0.002 * 26.6 ± 4.1 <0.001 * 29.3 ± 7.2 0.052
Body weight gained during pregnancy (kg) 10.2 ± 4.2 9.4 ± 6.2 0.231 9.8 ± 6.0 0.694 9.6 ± 6.5 0.423 7.1 ± 5.3 0.019 *
Gestational age at delivery (weeks) 38.7 ± 1.7 35.1 ± 4.0 <0.001 * 37.0 ± 2.7 <0.001 * 34.4 ± 4.1 <0.001 * 33.0 ± 5.5 0.004 *
Birth weight of the neonate (g) 3042.5 ± 479.7 2150.8 ± 863.9 <0.001 * 2565.5 ± 692.6 <0.001 * 1997.8 ± 833.1 <0.001 * 1835.9 ± 1156.0 0.003 *
Apgar score at 5 min 8.7 ± 0.8 7.7 ± 2.3 <0.001 * 8.5 ± 1.0 0.408 7.4 ± 2.5 <0.001 * 6.5 ± 3.0 0.027 *

Values of the continuous variables are expressed as the means ± standard deviation. HDPs: hypertensive disorders of pregnancy; GH: gestational hypertension; PE: pre-eclampsia; SPE: superimposed pre-eclampsia; BMI: body mass index. * p < 0.05.