Figure 7.
Details of the evolution of the bone repair process of the cranial defects at 14 days filled with biomaterial (G1/B), biocomplex consisting of biomaterial plus heterologous fibrin biopolymer (G2/BFB), biomaterial and PBM (G3/B + PBM), and biocomplex consisting of biomaterial plus heterologous fibrin biopolymer and photobiomodulation with low-level laser therapy (G4/BFB + PBM). The deposition of the osteoid matrix (asterisk) from the edges of the defect (b), particles of the biomaterial (B) interspersed with densely cellular reactive connective tissue (RT) and vascular budding (V). HE and Masson Trichrome; original magnification × 10; bar = 500 µm and insert, magnified images × 40; bar = 100 µm.