Table 3.

EVEREST II and COAPT clinical and echocardiography criteria for MitraClip™ device.

EVEREST Echocardiographic Criteria

Mitral valve orifice area > 4.0 cm2

Transvalvular gradient < 4 mmHg

Width of flail segment < 15 mm

Flail gap < 10 mm

Coaptation depth < 11 mm

Mobile leaflet length > 10 mm

COAPT Criteria

Secondary mitral regurgitation

At least one HF admission in the previous year or increased natriuretic peptide

NYHA ≥ II

Left ventricular ejection fraction (LVEF) 20–50%

Left ventricular end-systolic diameter ≤ 70 mm