Table 5.
Pathways Information | p-Value | miRNAs | |
---|---|---|---|
Fatty acids biosynthesis |
Synthesis of fatty acids. Fatty acids are generally excessive in the Western diet. |
2.1444 × 10−11 | hsa-miR-1254 |
Fatty acids metabolism |
Anabolic and catabolic processes involving fatty acids or related molecules. Fatty acids are generally excessive in the Western diet. |
0.0002 | hsa-miR-1254 |
Lysine degradation |
Catabolism of lysine (from dietary up-taken or intracellular proteins). Lysine is generally excessive in the Western diet. |
1.7153 × 10−7 | hsa-miR-505-5p; hsa-miR-302d-3p; hsa-miR-376a-5p; hsa-miR-302c-3p; hsa-miR-512-3p; hsa-miR-505-3p; hsa-miR-616-3p |
ECM–receptor interaction |
Tissue and organ morphogenesis; maintenance of cell and tissue structure and function; adhesion, migration, differentiation, proliferation, and apoptosis; force-transmitting physical link with the cytoskeleton. | <1 × 10−325 | hsa-miR-302c-5p; hsa-miR-184; hsa-miR-206; hsa-miR-635; hsa-miR-512-3p; hsa-miR-505-3p; hsa-miR-376a-3p |
ECM: ExtraCellular Matrix.