ABCB1	ATP Binding Cassette Subfamily B Member 1
ABCB11	ATP Binding Cassette Subfamily C Member 11
ABCC10	ATP Binding Cassette Subfamily C Member 10
ABCC2	ATP Binding Cassette Subfamily C Member 2
ABCC4	ATP Binding Cassette Subfamily C Member 4
ABCC5	ATP Binding Cassette Subfamily C Member 1
ADHD	attention deficit hyperactivity disorder
ADORA2A	Adenosine A2A Receptor
AIEOP	Associazione Italiana di Ematologia e Oncologia Pediatrica
ALL	acute lymphoblastic leukemia
ALL-BFM-95	ALL-Berlin–Frankfurt–Münster
Ara-G	Nelarabine
ara-GTP	ara-G triphosphate
Arg27His	amino acid arginine to histidine at codon 27
BBB	blood–brain barrier
BiTEs	dual-specific T-cell-binding antibodies
CD3	cluster of differentiation 3
CDA	Cytidine Deaminase
CEP72	Centrosomal Protein 72
CNS	central nervous system
COG	Pediatric Oncology Group
CR	complete response
Cri	a complete response with incomplete cell count recovery
CRP	C-reactive protein
CRS	cytokine release syndrome
CSF	cerebrospinal fluid
CTCAE	Common Terminology Criteria for Adverse Events
cTNS	clinical Total Neuropathy Score
CYP2C8	Cytochrome P450 Family 2 Subfamily C Member 8
CYP3A4	Cytochrome P450 Family 3 Subfamily A Member 4
CYP3A5	Cytochrome P450 Family 3 Subfamily A Member 5
DCK	Deoxycytidine Kinase
DHFR19bp	Dihydrofolate Reductase 19 bp polymorphism
ENT1	Equilibrative nucleoside transporter 1
GIT1	G Protein-Coupled Receptor Kinase Interacting ArfGAP 1
GM-CSF	granulocyte-macrophage colony stimulating factor
GRIA1	Glutamate Ionotropic Receptor AMPA Type Subunit 1
HLA-DRB1	Major Histocompatibility Complex Class II, DR Beta1
HSCT	allogeneic hematopoietic stem cell transplant (HSCT)
I.V.	intravenous
ICANS	immune effector cell-associated neurotoxicity syndrome
ICE	Immune Effector Cell-Associated Encephalopathy score
ICH	intracranial hemorrhage
ICOS	Inducible T-cell costimulator
ID-MTX	intermediate-dose methotrexate
InO	Inotuzumab
L-ASP	L-asparaginase
MAP4	Microtubule-Associated Protein 4
MRD	minimal residual disease
MTHFR 677C>T	Methylenetetrahydrofolate Reductase polymorphism
MTHFR 677TT	Methylenetetrahydrofolate Reductase polymorphism
MTX	methotrexate
MTX-NT	neurotoxicity associated with methotrexate
NO	nitric oxide
NT5C2	5’-Nucleotidase, Cytosolic II
NT5C3, 5’	Nucleotidase, Cytosolic IIIA
R/R	relapsed or refractory
RRM1	Ribonucleotide Reductase Catalytic Subunit M1
scFv	single-chain fragment variable
SLC19A1	Solute Carrier Family 19 Member 1
SLC5A7	Solute Carrier Family 5 Member 7
SNPs	Single nucleotide polymorphisms
SOS	sinusoidal obstruction syndrome
T-ALL	T-cell acute lymphoblastic leukemia
T-LBL	T-cell lymphoblastic lymphoma
TIT	triple intrathecal therapy
TUBB1	Tubulin Beta 1 Class VI
TUBB2A	Tubulin Beta 2A Class IIa
TUBB2B	Tubulin Beta 2B Class IIb
TUBB3	Tubulin Beta 3 Class III
TUBB4A	Tubulin Beta 4A Class Iva
TYMS	Thymidylate Synthetase
UKALL2003 trial	United Kingdom National Randomised Trial For Children and Young Adults with Acute Lymphoblastic Leukaemia and Lymphoma 2003
VCR	vincristine
VH	heavy chain variable gene segment
VL	variable region
VIPN	vincristine-induced peripheral neuropathy
ZBTB1	Zinc Finger and BTB Domain Containing 1