Table 3.

Comparison of different synthesis methods of graphene

Methods	Advantages	Disadvantages	Application	Ref
Micromechanical exfoliation	High quality and unmodified sheet synthesis, cost efficient, simple	Slow synthesis, small scale	Exploring properties of graphene	[49]
Liquid-phase exfoliation	Faster and large amount of graphene synthesis method	Hazardous solvents, chances of defects	Electrochemical biosensor	[52]
Chemical vapor deposition	Single or few layer graphene synthesis, large area sheets	Complex process, expensive	Biosensors	[53]
Reduction of graphene oxide	Low cost, easy and large-scale production	Unwanted defects, partially reversible	Amperometric biosensor	[54]
Laser scribed graphene	Controllable and inexpensive graphene production	Large number of defects, multilayer production	Electrochemical biosensor	[55]
3D graphene	Porous structure, high quality production, wide range of applications	Requirement of template, large number of defects	Electrochemical biosensor	[56]