Table 1.
CD4, CD8, regulatory and follicular T cell subsets in bronchoalveolar lavage (BAL), peripheral blood mononuclear cells (PBMC) and lymph nodes (LLN) from sarcoidosis patients.
| Parameters Mean ± SD | LLN | BAL | PBMC |
|---|---|---|---|
| CD4 (Th) | 67.1 ± 25.5 | 66.3 ± 16.3 | 55.1 ± 15.4 |
| CD4+CD103+ | 36.4 ± 22.6 | 37.0 ± 20.2 | 64.5 ± 25.1 |
| CD4+CXCR5+ (Tfh) | 0.755 ± 0.853 | 0.681 ± 0.724 | 0.302 ± 0.360 |
| Tfh CD103+ | 3.59 ± 3.77 | 5.80 ± 6.00 | 3.27 ± 2.29 |
| CD4+CD127+CD25+ (Th Effector) | 3.26 ± 3.41 | 1.08 ± 1.02 | 3.67 ± 3.44 |
| CD4+CD127+CD25− (Th Naive) | 43.8 ± 21.3 | 23.2 ± 21.1 | 51.5 ± 21.7 |
| CD4+CD25+CD127− (Th Reg) | 7.01 ± 3.97 | 7.01 ± 5.15 | 4.78 ± 2.92 |
| ThReg CD103+ | 34.2 ± 31.0 | 29.4 ± 28.8 | 60.8 ± 21.5 |
| CD8 (Tc) | 14.4 ± 12.6 | 21.8 ± 15.6 | 30.7 ± 12.8 |
| CD8+CD103+ | 0.751 ± 0.964 | 0.183 ± 0.449 | 0.910 ± 1.11 |
| CD8+CXCR5+ (Tfc) | 0.0817 ± 0.200 | 0.0390 ± 0.123 | 0.216 ± 0.285 |
| Tfc CD103+ | 0.0357 ± 0.0945 | 0.823 ± 1.15 | 0.134 ± 0.228 |
| CD8+CD127+CD25+ (Tc Effector) | 4.44 ± 4.39 | 1.32 ± 3.25 | 0.747 ± 0.865 |
| CD8+CD127+CD25− (Tc Naive) | 21.4 ± 12.9 | 10.4 ± 10.8 | 16.7 ± 11.4 |
| CD8+CD25+CD127− (Tc Reg) | 0.503 ± 0.649 | 1.01 ± 1.38 | 0.480 ± 0.565 |
| TcReg CD103+ | 5.00 ± 11.2 | 47.7 ± 43.5 | 6.03 ± 13.6 |
| CD4/CD8 ratio | 4.85 ± 4.33 | 3.10 ± 3.60 | 1.80 ± 1.42 |