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. 2022 May 20;12(5):838. doi: 10.3390/jpm12050838

Table 1.

Comparison of demographic and clinical characteristics among groups of multiple system atrophy patients with and without constipation.

Patients without Constipation
(n = 22)
Patients with Constipation
(n = 29)
p Value
Age (years) 65.3 ± 9.5 65.2 ± 11.1 0.434
Male (%) 40.9 56.5 0.503
Disease duration (years) 4.0 ± 2.7 4.9 ± 3.3 0.328
MMSE 26.6 ± 3.6 26.9 ± 2.5 0.718
LED (mg/day) 189.8 ± 344.3 244.3 ± 284.8 0.497
Laxative use (%) 22.7 55.2 0.019
Anti-cholinergic use (%) 0 0 n.s.

Data are presented as the mean ± SD. LED, levodopa equivalent dose; MMSE, Mini-Mental State Examination; n.s., not significant.