Table 1.

Summary of neuroprotective interventions for altered cerebral metabolism [29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44].

Intervention	Effect	References
Glucose/insulin	↑↓ glucose, ↑↓ LPR	[29,30,31,32,33]
Hyperoxia	↑ PBtO2, variable ↓ LPR	[34,35,36]
Hyperventilation	↓ glucose	[37,38]
Mannitol	↓ LPR	[32,39]
Decompressive craniotomy	↓ LPR	[43,44]
Therapeutic (induced) hypothermia	↓ glucose, ↓ lactate	[41,42]