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Integrated microfluidic exosome analysis directly from human plasma. (a) A photo of the prototype chip with the cascading microchannel for multi-stage exosome capture and analysis. (b) Schematic of the chip with the workflow. The numbers 1–4 indicate the inlet for exosome capture beads, washing/lysis buffer, protein capture beads, and ELISA reagents. (Reproduced from He M. et al. [75]. Copyright 2014, Lab Chip).
