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. 2022 Apr 30;13(5):730. doi: 10.3390/mi13050730

Figure 21.

Figure 21

Nanoplasmonic pillars engineered for single exosome detection (a) Picture of the 25.4 mm diameter LSPRi sensor chip. (b) Scanning electron microscope image of the device for a 20 × 20 array, with a pitch size of 600 nm scale bar: 1 μm. (c) Image of sixteen arrays, each consisting of 400 plasmonic nanopillars in a 20 × 20 square lattice and 500 nm pitch, scale bar: 10 μm. (d) False coloured SEM image of a 10 × 10 nanopillar array, scale bar: 1 μm. (e) High-magnification false-coloured SEM image showing a detailed view of individual nanopillars, scale bar: 200 nm. (f) Picture illustrating the size matching of individual nanopillars diameter (d = 90 nm) to that of exosomes (~50 nm < d < 200 nm). (Reproduced from Raghu D. et al. [87]. Copyright 2018, PLoS ONE).