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Schematic of the LSPR-based biosensor for the detection of the exosomes. (a) Fabricated gold nano-ellipsoid arrays on the quartz substrate. (b) Functionalization of the gold nano-ellipsoids with the Au–S bond. (c) Functionalization of anti-CD63 antibody (d) Exosomes injected into the microchannel and captured on the sensor substrate. (e) LSPR detecting platform (Reproduced with permission from Xiaoqing Lv et al. [88]. Copyright 2019, American Chemical Society).
