Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 19;15(5):495. doi: 10.3390/ph15050495

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Experimental design. Thirty-eight male Sprague-Dawley rats were purchased at 6 weeks of age, and cortical electrodes were implanted 1 week later for video-electrocorticographic (v-ECoG) recordings of recurrent seizures. Status epilepticus (SE) was induced with an intraperitoneal (i.p.) administration of kainic acid (KA; 15 mg/Kg) at 8 weeks of age (n = 2 rats died during the SE). Ten epileptic rats per group were treated with cannabidiol (CBD) at 12 mg/kg, 120 mg/kg, or with medium-chain triglyceride (MCT) oil. The remaining animals (n = 6) were used as control, non-treated rats.