Table 3.

Cell quantification results for both the monolayer and three-dimensional models using the trypan blue method.

Cell Line	Model	Mean—Fourth Day	Mean—Seventh Day	Mean—Tenth Day
A549	Monolayer	5.23 × 104 ± 7.56 × 103	8.50 × 104 ± 2.73 × 104	1.03 × 105 ± 2.08 × 103
	Spheroid	8.33 × 103 ± 2.36 × 103	1.23 × 104 ± 1.53 × 103	1.25 × 104 ± 2.08 × 103
MRC-5	Monolayer	1.91 × 105 ± 1.53 × 104	3.56 × 105 ± 3.96 × 104 (*)	3.06 × 105 ± 3.58 × 104
	Spheroid	2.69 × 103 ± 6.67 × 102	4.25 × 104 ± 3.75 × 103 (***)	3.13 × 104 ± 7.60 × 103 (**)

(*) p < 0.05; (**) p < 0.01; (***) p < 0.001. Values are expressed as the mean and standard deviation.