Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 26;14(5):936. doi: 10.3390/pharmaceutics14050936

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

SMM-189 treatment reduced the percentage of neutrophils during DSS-induced colitis. Spleens, MLNs, and LPLs were harvested from the three groups of mice described in the legend for Figure 1 and single-cell suspensions were prepared from each tissue. Cells were stained with antibodies specific for the T cell marker CD3 and the neutrophil marker LY6G. Panel (A), CD3⁻ lymphocytes from the spleen, MLNs, or LPLs were screened for the presence of neutrophils (LY6G) by flow cytometry. The percentage in the lower right quadrants of the plots in panel (A) reflects the total neutrophils and is shown in the bar graph of Panel (B). Data represents the total percentage of cells ± SEM from three independent experiments, each involving six mice per group (n = 18). Asterisks (*), indicate statistically significant differences (p < 0.01) between the vehicle (DSS) and SMM-189-treated groups.