Table 1.
Meso Perspective Group | Micro Perspective Group | References |
---|---|---|
Microorganism | Genetic modification or genetic identification | [4,6,10,13,14,15,18,21,22,29,30,31,32,39,43,45,46,47,51,53,55,56,57,60,61,62,65,74,75,81,85,86,89,90,92,93,95,110,113] |
Ks enzyme * | [6,10,13,14,15,29,35,43,53,55,57,62,87,93,97,104] | |
Resting cells, cell wall modifications or immobilization | [11,19,34,38,49,52,54,58,100,106,107,109] | |
Microbial selection | [24,37,70,71,89,91,96,101,109] | |
Process Improvement | Chemical addition | [11,17,18,20,22,23,27,28,33,38,39,40,44,48,49,52,59,63,69,72,73,78,80,82,83,84,94,98,99,100,102,103,106,107,111,112,114] |
Culture medium | [11,22,23,25,34,36,44,54,60,66,68,70,71,77,80,82,92,105,110,112,113,115] | |
Biphasic system | [19,23,27,42,44,66,68,73,78,82,83,94,99,114] | |
Operational mode or strategy | [13,14,16,44,45,50,79,101,104] | |
Process variables | [22,23,36,54,59,64,80,86,112,113] | |
Metabolic Intermediates and Hormones | PS ** or Co *** conversion into intermediates | [6,15,19,20,21,22,25,26,32,33,37,39,40,41,50,55,61,65,69,71,72,73,74,75,79,84,95,96,97,101] |
Hormone production from PS ** | [14,42,47,51,86,92,113] | |
Analytical Methods and others | Analytical methods | [12,67,88] |
Others | [76,108] |
* Ks enzyme: The enzymes 3-ketosteroid-9α-hydroxylase (Ksh) and 3-ketosteroid-1-dehydrogenase (KstD); ** PS: phytosterol; *** Co: cholesterol.